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Proteolytic enzymes (himopsin, chymotrypsin, trypsin)

Purpose
Active proteolytic enzymes decompose peptide bonds, contributing to the splitting of proteins into aminoacids and small peptides

Characteristics
Trypsin and chymotrypsin are proteolytic enzymes of the vertebrates pancreas. The first one splits peptide bonds at the residues Lys and Arg, while the second splits peptide bonds at the residues of Tyr, Phe and Trp. Himopsin is a complex of trypsin and chymotrypsin.


Physical and chemical characteristics:

A-chymotrypsin
[EC3.4.21.1]
Mr25000
• freeze- dehydrated white powder
• specific activity – 25 TE
• pH stability 4,56,5

Trypsin
[EC3.4.21.4]
Mr23000
• freeze-dehydrated powder or porous mass of white with a slightly yellowish tinge
• specific activity – 48 TE
• pH stability 3,05,5

Himopsin
• complex of proteolytic enzymes (chymotrypsin and trypsin)
• specific activity – 59 TE
• pH stability 4,56,5

Application
Spheres of applications of proteolytic enzymes are quite extensive. They are used in laboratory and diagnostic practice, medicine, agriculture, etc.

Laboratory and diagnostic practice:
1.Selective reagents in structural studies of proteins:
• chemical-enzymatic synthesis
• racemate division
• resynthesis of peptide and ester linkage
2. "Reinforcing" enzyme markers at the immune-enzyme microanalysis
3. Cell cultures sampling

Medicine:
1. As a medicament the treatment of:
  • thrombophlebitis
  • necrotic ulcers
  • bronchial asthma
2. Replacement therapy substances
3. Enzymatic cleaning of contact lenses

Agricultural and food industry:
  • cheesemaking
Commercial offer
Substances and solutions delivery